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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHX
All Species:
12.73
Human Site:
T250
Identified Species:
20
UniProt:
O00330
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00330
NP_001128496.1
501
54122
T250
A
P
S
P
L
Q
A
T
A
G
P
S
Y
P
R
Chimpanzee
Pan troglodytes
XP_001149489
501
54051
T250
A
P
S
P
L
Q
A
T
A
G
P
S
Y
P
R
Rhesus Macaque
Macaca mulatta
XP_001109997
446
48686
E219
R
R
S
G
T
F
T
E
I
P
A
S
N
I
R
Dog
Lupus familis
XP_533153
501
54075
T250
V
P
L
P
P
Q
A
T
A
T
P
P
Y
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKZ9
501
53981
T250
A
S
V
P
P
Q
A
T
A
G
P
S
Y
P
R
Rat
Rattus norvegicus
P08461
632
67147
P380
K
D
I
D
S
F
V
P
T
K
A
A
P
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026358
502
53201
A249
P
S
A
L
P
A
A
A
V
P
S
A
Y
P
R
Frog
Xenopus laevis
NP_001087423
478
50485
F235
P
V
S
G
R
L
T
F
P
P
M
S
I
P
G
Zebra Danio
Brachydanio rerio
NP_956854
490
51982
P243
A
P
A
P
P
A
A
P
P
A
A
R
P
T
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624025
598
64649
Q349
T
A
P
P
P
K
D
Q
K
Q
P
D
I
P
L
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
A262
S
Q
A
P
A
K
G
A
T
S
T
T
T
Q
A
Sea Urchin
Strong. purpuratus
XP_001177721
482
51019
A237
A
A
A
P
P
A
P
A
P
P
T
V
Q
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WQF7
637
68844
S347
L
E
H
G
L
E
A
S
S
I
E
A
S
G
P
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
G240
A
T
S
S
T
T
A
G
S
A
P
S
P
S
S
Red Bread Mold
Neurospora crassa
P20285
458
48601
P231
A
A
A
Y
T
D
V
P
I
S
G
M
R
K
T
Conservation
Percent
Protein Identity:
100
99.5
87
90.2
N.A.
85.2
34.4
N.A.
N.A.
72.1
58.8
58
N.A.
N.A.
36.4
37.2
47.3
Protein Similarity:
100
99.8
87.6
93.2
N.A.
91.4
49.6
N.A.
N.A.
82
73.4
73
N.A.
N.A.
51.6
56.7
63
P-Site Identity:
100
100
20
60
N.A.
80
0
N.A.
N.A.
26.6
20
26.6
N.A.
N.A.
20
6.6
20
P-Site Similarity:
100
100
20
60
N.A.
80
6.6
N.A.
N.A.
40
20
33.3
N.A.
N.A.
26.6
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.9
32.7
34.7
Protein Similarity:
N.A.
N.A.
N.A.
48.9
51.9
51.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
33.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
40
40
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
20
34
0
7
20
54
20
27
14
20
20
0
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
0
7
7
0
0
0
0
7
0
0
0
% D
% Glu:
0
7
0
0
0
7
0
7
0
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
14
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
20
0
0
7
7
0
20
7
0
0
7
7
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
7
0
0
0
0
0
14
7
0
0
14
7
0
% I
% Lys:
7
0
0
0
0
14
0
0
7
7
0
0
0
7
0
% K
% Leu:
7
0
7
7
20
7
0
0
0
0
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
14
27
7
54
40
0
7
20
20
27
40
7
20
47
14
% P
% Gln:
0
7
0
0
0
27
0
7
0
7
0
0
7
7
0
% Q
% Arg:
7
7
0
0
7
0
0
0
0
0
0
7
7
0
40
% R
% Ser:
7
14
34
7
7
0
0
7
14
14
7
40
7
14
7
% S
% Thr:
7
7
0
0
20
7
14
27
14
7
14
7
7
7
7
% T
% Val:
7
7
7
0
0
0
14
0
7
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
34
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _